同种异体骨软骨移植修复软骨损伤的研究进展

Osteochondral allografts in articular cartilage repair

关节软骨损伤的治疗是骨科领域一个难题,同种异体骨软骨移植是修复全层软骨损伤的有效方法。文中综述了同种异体骨软骨移植修复软骨损伤的研究进展,包括该方法的适应证和禁忌证,目前在临床的应用情况及治疗效果,并进一步探讨了同种异体骨软骨移植中的3个热点话题,如疾病传播、免疫排斥和移植物的保存。这些文献综述显示同种异体骨软骨移植修复关节软骨损伤具有特定优势,但进一步推广该方法仍有一些需要解决的问题。

Articular cartilage injury is a problem in the field of orthopedics, osteochondral allografis transplantation is an ef- fective way in the treatment of articular cartilage injuries. The article summarizes the research advances of osteochondral allograft transplantation, including the indication and contraindication of the methods, currently application in clinical treatment, and further exploring three hot topics in the osteochondral allograft transplantation, such as the spread of diseases,immune rejection and graft preservation. These literature review showed that osteoehondral allograft transplantation to repair cartilage damage has a specific advantage, but still has some problems for further promoting.