有氧锻炼对于鼻咽癌患者放疗疲劳的干预效果

The effect of aerobic exercise on refieving fatigue radiotherapy

目的探讨有氧锻炼对于鼻咽癌患者放疗疲劳的干预效果。方法将63例接受放疗的早中期鼻咽癌患者随机分为干预组32例和对照组31例。对照组接受常规护理和随意锻炼，干预组在此基础上于放疗第2周开始实施连续4周的有氧锻炼。在放疗第1周和第5周每日填写简明疲劳量表，分别计算即时疲劳、一般疲劳和最严重疲劳的平均评分，比较两组患者锻炼前后3类疲劳评分的差异。结果锻炼前两组患者3类疲劳评分差异均无统计学意义，锻炼后干预组3类疲劳评分均显著低于对照组；组内比较，干预组即时疲劳、一般疲劳评分锻炼后均高于锻炼前，但锻炼前后最严重疲劳评分差异无统计学意义；对照组3类疲劳评分锻炼后均高于锻炼前。结论有氧锻炼干预能有效缓解鼻咽癌患者的放疗疲劳。

Objective To explore the effect of aerobic exercise on relieving fatigue of nasopharyngeal carcinoma patients received radiotherapy. Methods A total of 70 hospitalized patients with nasopharyngeal carcinoma of early and middle clinical stages were randomly divided into intervention group and control group （35 in each）. Patients in control group received regular nursing while patients in intervention group were instructed to carry out aerobic exercise which began at the 2nd week of radiotherapy program （ walked 20min daily and lasted for 4 weeks） besides receiving regular nursing. All patients completed the Brief Fatigue Inventory （BFI） themselves in the first week and the 5th week of radiotherapy program and the fatigue severity before and after exercise was respectively represented as average fatigue score in these two weeks. The fatigue severity of patients in two groups before and after exercise was compared according to three types of fatigue （ current fatigue, fatigue of usual level and the worst level during past 24 hours）. Results There was no significant difference between fatigue score of all three types in two groups before aerobic exercise （P〉0. 05）. After exercise, the score of three types in control group was markedly higher than intervention group （P 〈0. 01）. Though the score of current and usual fatigue were increased after exercise in intervention group （P 〈0.01）, the score of the worst fatigue after exercise showed no significantly different compared to that before exercise （ P 〉0. 05 ）. Conclusions Aerobic exercise is an effective method to relieve radiotherapy related fatigue of patients with nasopharyngeal carcinoma.