老年心力衰竭患者B型脑钠肽水平与心肌功能指数的关系

Relationship between B-type natriuretic peptide and Tei index in elderly patients with heart failure

目的探讨老年心力衰竭（HF）患者B型脑钠肽（BNP）水平与Tei指数的关系。方法检测65例老年心力衰竭患者及30例健康对照组血浆BNP水平；同时采用彩色多普勒超声仪测定系列超声参数，计算Tei指数。结果HF患者的血浆BNP水平和Tei指数明显高于对照组（P〈0．01），且随着NYHA心功能分级的加重，HF患者的血浆BNP水平和Tei指数呈逐级明显增高（P〈0．01）；HF患者血浆BNP水平与Tei指数呈正相关（r=0．517，P〈0．05）。结论血浆BNP水平与Tei指数可作为判定老年HF严重程度的临床指标，且两者具有良好的相关性。

Objective To study the relationship between B-type natriuretic peptide and Tei index in elderly patients with heart failure（HF）. Methods The plasma BNP levels in elderly patients with HF（ n = 65 ） and normal control group（ n = 30） were measured ; at one time, series of ultrasonic parameters were measured by the color Doppler ultrasound,counting up Tei index. Results The plasma BNP levels and Tei index in elderly patients with HF were significantly higher than those in control group（ P 〈0.01 ） ,with NYHA cardiac function classification aggravating, they were significantly higher by levels（P 〈0. 01 ） ; the plasma BNP levels were positively related to Tei index（ r = 0. 517,P 〈 0. 05）. Conclusion Plasma BNP levels and Tei index can be used as clinical indicators to determine the serious degree of elderly HF, and they have good correlation.