摘要
近年来,基因、分子、细胞、影像等实验证据表明抑郁症是和应激密切相关的反复发作的慢性脑疾病,其主要临床症状涉及情绪、奖赏、认知等高级脑功能。随着抑郁症神经生物学研究的深入,基因与环境相互作用导致神经可塑性改变将成为揭示"抑郁大脑"的重要途径,为抑郁症的预防与治疗提供新思路和新途径。
Depression is a recurrent and chronic mood disorder indi- cated by the evidences combining gene, molecular, cellular and im- aging. The symptoms of depression are related to the higher brain function, such as emotion, reward and cognition. The convergence of gene-environment interaction and neuroplasticity may provide a more general understanding of pathophysiology of depression and new approaches to antidepressant.
出处
《自然杂志》
北大核心
2009年第3期148-152,共5页
Chinese Journal of Nature
