实时三维超声心动图评价高血压患者左心室心肌质量及左心房功能

Assessment of left ventricular mass and left atrial function by using real-time three-dimensional echocardiography in patients with hypertension

目的应用实时三维超声心动图技术评价高血压患者左心室质量、左心房功能,并对左心室质量的测量与常规M型方法进行对照。方法在37名健康人、39例高血压无左心室肥厚(NLVH)患者和27例高血压伴左心室肥厚(LVH)患者中进行了超声心动图检查。应用M型超声心动图测量左心室质量(LVM)并计算左心室质量指数(LVMI),实时三维超声测量左心室质量(LVM)及LVMI,左心房舒张末容积(LAEDV)、左心房收缩末容积(LAESV),左心房射血分数(LAEF),并比较高血压组(NLVH组、LVH组)与健康对照组之间的差异。结果对照组、高血压NLVH组、LVH组3组间左心室质量指数两种检测方法差异均具有统计学意义(P<0.05),并且发现三维超声检测结果较M型测量数值低。左心房收缩功能指标各组间差异均有统计学意义(P<0.05)。在左心室重构、心肌质量增大的高血压患者,左心房容积增大,而收缩功能减低。结论实时三维超声技术能够定量评价高血压患者左心房功能,测量左心室质量。

Objective To assess left ventricular mass and left atrial function in patients with hypertension by using real-time three-dimensional eehocardiography （RT-3DE）. Methods Sixty-six patients with hypertension and thirty seven normal subjects （control group） were enrolled. Hypertensive patients were divided into left ventficular hypertrophy （I.VH） group and non-left ventricular hypertrophy （NLVH） group. Philips iE-33 with X3-1 probe was used to perform full volume real-time three-dimensional echocardiography, and then were analyzed offline by Qlab software. The left ventricular mass, left atrial ejection fraction（LAEF） were derived. Results Left ventricular mass increased in LVH group and NLVH group than in control group （ P 〈 0. 05 ）. And left ventricular mass obtained by M-mode echocardiography was greater than that by RT-3DE. Compared with control group, I.AEF decreased in LVH group and NLVH group （ P 〈 0. 05 ）. Conclusions RT- 3DE can evaluate left ventricular mass and left atrial function quantitatively in patients with hypertension.