某城市社区老年抑郁症危险因素的1∶4配比病例对照研究

A 1∶4 matched case-control study on risk factors of elderly depression in urban communities

目的探讨某城市社区老年抑郁症发生的可能危险因素。方法对24例诊断患有抑郁症的老年人和96例无抑郁症的老年人进行1∶4配比的病例对照研究,采用χ2检验和条件Logistic回归等分析方法对数据进行统计分析。结果单因素分析显示自评经济、自评健康、负性生活事件、居住模式4个因素在两组间的差异有统计学意义(P<0.05),多因素分析证实了在去除年龄、性别、居住地的影响后,自评经济、自评健康、负性事件、居住模式4个因素仍与老年抑郁症的发生显著相关,OR值(95%CI)分别为,5.151(1.031～25.722);4.134(1.017～16.082);3.595(1.170～11.048);6.645(1.736～25.436)。结论自评经济收入状况不满意、自评健康状况差、近半年出现负性生活事件、独居为老年抑郁症的重要危险因素。

Objective To explore the possible risk factors of elderly depression in Urban Community. Methods A 1：4 matched case-control study including 24 elders with depression and 96 non-depressive elders in Hefei urban communities was conducted. Data were analyzed by statistical technique of Chisquare test and conditional logistic regression. Results Univariate analysis showed that self-perceived economy, self-perceived health, negative life events, living mode had significant difference between the 2 groups （P〈 0.05）. Multivariate analysis confirmed that self-perceived economy, self-perceived health, negative life events, living mode were significantly related to elderly depression, and their OR （95 % confidence interval） were 5. 151（1.031-25.722）, 4. 134（1.017- 16. 082）, 3. 595（1.170- 11. 048）, 6. 645 （ 1. 736- 25. 436）, respectively. Conclusions The self-perceived poor economy, self- perceived poor health, negative life events happened in recent half a year, living with non-lineal family members, were important risk factors of elderly depression.