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系统性红斑狼疮患者自身抗体检测的临床评价

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摘要 目的:探讨自身抗体对系统性红斑狼疮(SLE)诊断价值和临床意义。方法:本文用酶免吸附(ELISA)法和免疫印迹技术(IBT)对200例SLE患者的血清进行检测,抗核抗体(ANA)用酶免吸附(ELISA)法,ENA多肽抗体用IBT,同时通过探讨ANA和核抗原(ENA)多肽谱对SLE的诊断价值和临床意义。结果:其中Sm阳性率47%,URNP/Sm阳性率44%,SSA阳性率69%,SSB阳性率28%,His-tone阳性率50%,RO-52阳性率8%,Rib阳性率18.7%,NUKL阳性率62.5%,ANA阳性率为98%。结论:检测ENA多肽抗体对以上SLE的诊断、预后有一定的临床价值。
作者 曾文 安坤
出处 《现代医药卫生》 2009年第13期1979-1981,共3页 Journal of Modern Medicine & Health
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