期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

离体心脏保存技术的研究进展 被引量：1

Research Progress of Technologies of the Isolated Heart Preservation
下载PDF
导出
摘要 心脏保存在心脏移植过程中维持离体心脏的正常生理功能扮演重要的角色。改进供心的保存技术可以延长供心的保存时间，扩大供心的来源。本文简介了心脏保存的现状和原则；总结了各种离体心脏保存方法，从保护离体心脏功能的角度分析各种保存方法的机制和优缺点。但是，目前心脏保存并没有取得实质性进展，在一些方面仍然存在诸多不明和争议，尚需进一步探究。 Heart preservation plays an important role to maintain the normal physiological functions of isolated heart in the process of heart transplantation. For the heart preservation,improving the technology car extend the time of the preservation and the source of the donor heart. This article introduced the current situation and the principle of heart preservation, and summarized kinds of preservation methods for donor heart, their advantages and disadvantages, and their mechanisms in protection of heart function. However, the hear preservation need further reasearch.
作者 贺铭 曹西南
机构地区 昆明医学院基础医学院分子生物学实验室
出处 《医学综述》 2009年第13期1992-1994,共3页 Medical Recapitulate
关键词 心脏移植 心脏保存 研究进展 Head transplantation Heart preservation Research progress
分类号 R282.71 [医药卫生—中药学] R617 [医药卫生—外科学]
  • 相关文献

参考文献17

  • 1Jahania MS, Sanchez JA, Narayan P, et al. Heart preservation for transplantation:principles and strategies [ J ]. Ann Thorac Surg, 1999,68 (5) : 1983-1987.
  • 2Toledo-Pereyra LH,Rodriguez FJ. Scientific basis and current status of organ preservation [ J ]. Transplant Proc, 1994,26 ( 1 ) :309 -311.
  • 3McLaren A J, Friend PJ. Trends in organ preservation [ J ]. Transpl Int,2003,16(10) :701-708.
  • 4Hoenieke EM,Sun X, Strange RG Jr, et al. Donor heart preservation with a novel hyperpolarizing solution:superior protection compared with university of Wisconsin solution [ J ]. J Thorac Cardiovas Surg, 2000,120 ( 4 ) : 746-754.
  • 5Jovanovic S,Jovanovic A. Pinacidil prevents membrane depolarization and intracellular Ca^2+ loading in single cardiomyocytes exposed to severe metabolic stress [ J ]. Int J Mol Med, 2001,7 (6) : 639-643.
  • 6郭炜,沈岳良,陈莹莹,胡志斌,严志焜,夏强.二氮嗪在长时程心脏低温保存中的作用[J].生理学报,2004,56(5):632-638. 被引量：10
  • 7陈建明,范士志,李寒,蒋耀光,李坤.附加二氮嗪与1,6-二磷酸果糖心麻痹液对冷保存大鼠心脏缺血再灌注损伤的保护作用[J].创伤外科杂志,2006,8(4):352-354. 被引量：2
  • 8高宏,臧旺福.心脏移植供心的保护[J].国际心血管病杂志,2006,33(4):220-222. 被引量：2
  • 9Rosenbaum DH, Peltz M, Merritt ME, et al. Benefits of perfusion preservation in canine hearts stored for short internals [ J ]. J Surg Res,2007,140(2) :243-249.
  • 10Rosenbaum DH, Peltz M, DiMaio JM, et al. Perfusion preservation versus static preservation for cardiac transplantation:effects on myocardial function and metabolism [ J ]. Organ Preserv, 2008, 27 (1) :93-99.

二级参考文献45

  • 1陈建明,范士志,李寒.二氮嗪与1,6-二磷酸果糖伍用对大鼠心脏保存作用的初步研究[J].重庆医学,2006,35(1):40-42. 被引量：3
  • 2[1]Chien S, Zhang F, Niu W, Ehringer W, Chiang B, Shi X, Gray LA Jr. Fructose-1,6-diphosphate and a glucose-free solution enhances functional recovery in hypothermic heart preservation. J Heart Lung Transplant 2000; 19(3): 277-285.
  • 3[2]Cropper JR, Hicks M, Ryan JB, Macdonald PS. Cardioprotection by cariporide after prolonged hypothermic storage of the isolated working rat heart. J Heart Lung Transplant 2003;22(8): 929-936.
  • 4[4]Fu C(傅琛),Cao CM,Xia Q,Yang J,Lu Y.Reactive oxygen species and mitochondrial KATP-sensitive channels mediated cardioprotection induced by TNF-αduring hypoxia and reoxygenation. Acta Physiol Sin(生理学报)2003;55(3):284-289.
  • 5[5]Garlid KD, Paucek P, Yarov-Yarovoy V, Murray HN,Darbenzio RB, D'Alonzo AJ, Lodge NJ, Smith MA, Grover GJ. Cardioprotective effect of diazoxide and its interaction with mitochondrial ATP-sensitive K+ channels. Possible mechanism of cardioprotection. Circ Res 1997; 81(6): 1072-1082.
  • 6[6]Liu Y, Sato T, O'Rourke B, Marban E. Mitochondrial ATP-dependent potassium channels: novel effectors of cardioprotection? Circulation 1998; 97(24): 2463-2469.
  • 7[7]Wang Y, Ashraf M. Role of protein kinase C in mitochondrial KATP channel-mediated protection against Ca2+ overload injury in rat myocardium. Circ Res 1999; 84(10): 1156-1165.
  • 8[8]Toyoda Y, Levitsky S, McCully JD. Opening of mitochondrial ATP-sensitive potassium channels enhances cardioplegic protection. Ann Thorac Surg 2001; 71(4): 1281-1288.
  • 9[9]Akao M, Ohler A, O'Rourke B, Marban E. Mitochondrial ATP-sensitive potassium channels inhibit apoptosis induced by oxidative stress in cardiac cells. Circ Res 2001; 88(12):1267-1275.
  • 10[10]Wakiyama H, Cowan DB, Toyoda Y, Federman M, Levitsky S, McCullyJD. Selective opening of mitochondrial ATP-sensitive potassium channels during surgically induced myocardial ischemia decreases necrosis and apoptosis. Eur J Cardiothorac Surg 2002; 21(3): 424-433.

共引文献18

同被引文献20

  • 1李刚,张倞,张杨杨,张小虎,王永武.兔腹腔异位心脏移植模型的建立方法比较[J].同济大学学报（医学版）,2007,28(6):44-48. 被引量：1
  • 2Hatayama N,Naito M,Hirai S,et al.Preservation by desiccation of isolated rat hearts for 48 hours using carbon monoxide(PCO=4,000 h Pa)and oxygen(PO(2)=3,000h Pa)[J].Cell Transplant,2012,21(2-3):609-615.
  • 3庄红明,朱洪荫,牛星焘,等.家兔同种心脏异位移植术[J].中国病理生理杂志,1988,4(1):60-62.
  • 4Esper E,Filer S R,Wardrip C L,et al.Modified technique for abdominal heterotopic cardiac transplantation in the rabbit[J].Lab Anim Sci,1998,48(2):201-205.
  • 5Makowka L,Zerbe T R,Chapman F,et al.Prolonged rat cardiac preservation with UW lactobionate solution[J].Transplant Proc,1989,21(1 Pt 2):1350-1352.
  • 6Gaubin-Blanquet Y,Pianezzi B,Massue J P.Influence of various physical factors on the developmental capacities of the ovum of Artemia salina[J].C R Seances Soc Biol Fil,1976,170(6):1305-1301.
  • 7Tenhunen R,Marver H S,Schmid R.The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase[J].Proc Natl Acad Sci U S A,1968,61(2):748-755.
  • 8Chien J W,Sullivan K M.Carbon monoxide diffusion capacity:how low can you go for hematopoietic cell transplantation eligibility?[Z].2009,15(4):447-453.
  • 9Bojakowski K,Gaciong Z,Grochowiecki T,et al.Carbon monoxide may reduce ischemia reperfusion injury:a case report of complicated kidney transplantation from a carbon monoxide poisoned donor[J].Transplant Proc,2007,39(9):2928-2929.
  • 10Hirano K,Sato Y,Kobayashi T,et al.Carbon monoxide hemoglobin and bilirubin metabolism in adult living-related liver transplantation[J].Hepatogastroenterology,2003,50(54):1745-1748.

引证文献1

二级引证文献1

医学综述
2009年 第13期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部