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Etanercept对类风湿关节炎患者血清MMP-3的影响 被引量：1

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摘要 目的观察Etanercept治疗对类风湿关节炎(RA)患者血清基质金属蛋白酶3(MMP-3)的影响。方法16例RA患者,采用Etanercept治疗36周,应用ELISA法分别检测治疗前及治疗后1、2、4、8、12、24、36周外周血清中MMP-3的水平变化。结果Etanercept治疗2周后,MMP-3水平即较基线明显下降(P<0.01),第12周后下降至最低点。结论Etanercept治疗可使活动性RA患者外周血MMP-3水平下降,可用于监测患者的治疗反应。
作者 杨西瑞
机构地区 胜利油田中心医院
出处 《山东医药》 CAS 北大核心 2009年第24期91-92,共2页 Shandong Medical Journal
关键词 关节炎 类风湿 基质金属蛋白酶3 酶联免疫吸附测定
分类号 R593.22 [医药卫生—内科学]
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参考文献8

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二级参考文献22

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共引文献39

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山东医药
2009年 第24期

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