86例冠心病患者踝臂指数及其相关危险因素研究

Clinical study of ankle brachial Index and related risk factors in 86 patients with coronary artery disease

目的了解冠心病患者踝臂指数(ABI)异常率,探索冠心病患者ABI异常的危险因素。方法对本院2007年冠心病住院患者(冠心病组)和冠状动脉造影正常的非冠心病患者(对照组)进行ABI测量,ABI<0.9可诊断为外周动脉疾病(PAD),同时收集患者性别、年龄、伴随疾病等相关资料。对收集到的资料采用logistic回归模型进行分析。结果冠心病组和对照组ABI异常率分别为48.84%、28.75%;ABI异常与冠心病患者年龄、性别、糖尿病、心肌梗死和颈动脉斑块有关;70岁年龄组ABI异常率明显高于其他年龄组;ABI异常率在不同性别之间差异有统计学意义,男性明显高于女性(χ2=12.89,P=0.003 5)。结论在冠心病患者中ABI异常的发生率较高,70岁高龄、糖尿病、高血脂症及颈动脉粥样硬化斑块形成等为冠心病ABI异常(合并PAD)的危险因素。

Objective To study the abnormal ankle brachial index（ABI） and related risk factors in hospitalized patients with coronary artery disease（CAD）. Methods Evaluated the ABI in 86 hospitalized patients（from January 1st to December 1st in 2007） with CAD and in 80 patients without CAD,peripheral arterial disease（PAD） was defined as ABI≤0.9. Results The prevalence of abnormal ABI in CAD was 48.84%, and our study showed, ABI was influenced by age, sex, diabetes mellitus,myocardial infarction and plaque of carotid atherosclerosis. The prevalence of abnormal ABI was higher in aged patients, especially in patients of （75.29 ± 3.61） years old. The prevalence of abnormal ABI of men was obviously higher than that of women. Conclusion To make noninvasive measures of ABI to diagnose early PAD is safe, effective and simple. Our study showed, the prevalence of abnormal ABI was higher in patients with CAD（almost 1/2）, and most of the patients suffered ages, diabetes mellitus,and plaque of carotid atherosclerosis.