中药酸枣仁的化学成分研究

Studies on the chemical constituents of the Seeds of Zizyphus jujuba Mill

目的：研究酸枣仁的化学成分。方法：采用乙醇提取，硅胶、SephadexLH-20柱色谱等方法分离纯化，根据理化性质和波谱方法鉴定化合物的结构。结果：从酸枣仁中分离得到7个化合物，分别鉴定为豆甾4-烯-3-酮（Ⅰ）、苯丙氨酸（Ⅱ）、甘油（Ⅲ）、异当药黄素（Ⅳ）、正二十六酸（Ⅴ）、槲皮素（Ⅵ）、齐墩果酸（Ⅶ）。结论：化合物Ⅴ～Ⅶ为首次从该植物中分离得到。

Objective ： To study the chemical constituents of the seeds of Zizyphus jujuba Mill. Methods ： Multi-chromatographic methods including silica gel column chromatography and Sephadex LH-20 gel permeation were employed for the isolation and purification. The structures were identified on the basis of chemical reaction and spectral analisis. Results ： Seven compounds were isolated and identified as stigmast-4-en-3-one, phenylalanine, glycerol, isoswertis, hexacosanoic acid, quercetin and nolic acid. Conclusion： Compound 5,6 and 7 were isolated from the seeds of Zizyphus jujuba Millfor the first time.