血清ADA与HA、PⅢP联检在乙型肝炎中的变化及临床意义

Clinical Significance of Combined Determination of the Changes of the Serum ADA,HA and PⅢP Levels in Patients with Hepatitis B

目的:探讨了血清腺苷脱氨酶(ADA)与HA、PⅢP联检乙型肝炎中的变化及临床意义。方法:应用生化法和放射免疫分析对102例乙型肝炎患者进行了血清ADA和HA、PⅢP检测,并与35名正常健康人作比较。结果:乙型肝炎患者血清ADA、HA、PⅢP水平均非常显著地高于正常人组(P<0.01),尤以肝硬化为甚(P<0.01)。结论:检测乙型肝炎患者血清中ADA和HA、PⅢP水平的变化,对了解病情、观察预后均有重要的临床价值。

Objective To explore the clinical significance of the changes of serum ADA, HA and PllI P levels in patients with hepatitis B. Methods Serum adenosine deaminase （ADA） （ with biochemistry） and HA Pill P （ with R/A） levels were determined in 102 patients with hepatitis B of various stages and 35 controls. Results Serum ADA, HA and PⅢP levels in patients with hepatitis B were significantly higher than those in controls （ P 〈 0.01 ）. Particularly in patients with cirrhosis （ n = 13 ） （ P 〈 0.001 ）. Conclusion The serum ADA, HA and PⅢP levels were closely related to the diseases process of hepatitis B and were of great clinical values.