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青霉烯类抗生素的分子结构修饰

Molecular Modification of Peneme Structure
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摘要 综述了青霉烯类抗生素C-2位的分子结构修饰情况,分析了通过C,S或N等原子连接一些特殊官能团的青霉烯类化合物的构效关系.通过C原子和其他官能团连接的青霉烯类化合物活性较好,是一类有应用价值的化合物. An overall description of molecular modification of Penem structure at C-2 is presented. Special attention is given to the structure-activity relationship analysis of peneme compounds whose special functional groups are connected by atom C, S and N. Peneme compounds whose functional groups are connected through atom C have better chemical activity. It is a kind of useful compounds with certain utility value.
作者 崔秋兵 王碧
机构地区 内江师范学院化学与生命科学学院
出处 《内江师范学院学报》 2009年第6期29-32,39,共5页 Journal of Neijiang Normal University
关键词 青霉烯 分子结构修饰 构效关系 penemes, molecular modification, structure-activity relationship
分类号 R978.11 [医药卫生—药品]
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参考文献32

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内江师范学院学报
2009年 第6期

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