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尿苷肽类抗生素sansanmycin E的分离、纯化和结构鉴定 被引量：3

Isolation,purification and structure determination of uridylpeptide antibiotic sansanmycin E
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摘要 目的从Streptomyces sp SS产生的尿苷肽类抗生素sansanmycins复合物中分离、提取和纯化小组分的尿苷肽类化合物,并进行结构鉴定。方法利用大孔树脂吸附、反相制备HPLC等方法进行分离纯化。利用光谱分析,进行结构解析。结果分离到一个尿苷肽类化合物sansanmycin E。结论经鉴定sansanmycin E为新结构化合物。 Objective To isolate and purify the minor components from sansanmycins produced by Streptomyces sp SS and determine their structures. Method Sansanmycin E was isolated and purified by means of various chromatographies, such as macroporous adsorptive resins, reverse-phase preparative HPLC, etc. Its structure was elucidated by spectroscopic analyses. Result A uridyljpeptide antibiotic sansanmyein E was obtained. Conclusion Sansanmyein E was identified as a novel compound.
作者 解云英 许鸿章 俞莹 陈汝贤
机构地区 中国医学科学院北京协和医学院医药生物技术研究所
出处 《中国抗生素杂志》 CAS CSCD 北大核心 2009年第6期326-328,共3页 Chinese Journal of Antibiotics
关键词 Sansanmycin E 尿苷肽类 Sansanmycins Sansanmycin E Uridylpeptides Sansanmycins
分类号 R978.19 [医药卫生—药品]
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参考文献5

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二级参考文献10

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中国抗生素杂志
2009年 第6期

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