聚乙二醇相转移催化合成3-硝基水杨醛

Synthesis of 3-Nitrosalicylaldehyde Using Polyethylene Glycol as a Phase Transfer Catalyst

在醋酸、相转移催化剂聚乙二醇-400存在下,水杨醛与硝酸铈铵反应生成3-硝基水杨醛。最佳反应条件为:n(水杨醛)∶n(硝酸铈铵)∶n(聚乙二醇-400)=1∶1∶0.056,反应温度为40℃,反应时间为1.6 h,产率达76.6%。聚乙二醇-400可循环使用5次,催化活性基本不变。

In the presence of acetic acid and polyethylene glycol, salicylaldehyde reacted with ceric ammonium nitrate to from 3-nitrosalicyaldehyde. The optimal reaction conditions were. n（salieylaldehyde） ：n（ceric ammonium nitrate）：n（PEG-400）=1：1：0. 056, reaction temperature of 40℃ and reaction time of 1.6 h. The yield of 3-nitrosalicyaldehyde was 76.6%. The catalyst could be reutilized up to five times with little decrease in activity.