摘要
N-甲基-1,2-苯并异噻唑啉-3-酮是一种广谱高效的杀菌剂,以邻氨基苯甲酸为原料,经重氮二硫代、酰氯化、氮酰化、Zincke二硫化物分裂以及碱性条件下环合五步反应制得目标产物,总收率为53.5%,产品含量≥99%,产品结构经红外、核磁得到确认。
N-Methyl-benzisothiazolin-3-one is a kind of broad-spectrum and efficient fungicide.s. It was prepared from o-aminobenzoic acid by diazotization and disulfurization, chloridization, N-Acylation, Zincke disulfide cleavage and ring-closure reaction in alkaline solution. The total yield was 53.5 %. The content of the product was more than 99%. The structure of product was identified by IR and ^1H NMR spectroscopy.
出处
《化学世界》
CAS
CSCD
北大核心
2009年第6期361-363,共3页
Chemical World
