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间充质干细胞在移植中的作用 被引量：1

Effect of mesenchymal stem cell in transplantation
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摘要 间充质干细胞（MSC）是一类具有高度自我更新及多向分化潜能的组织干细胞，易于在体外扩增，在造血干细胞移植（HSCT）及其他系统的移植中发挥重要的作用。详细阐述了MSC支持造血、促进植入，调节免疫及减轻移植后的移植物抗宿主病（GVHD）等方面的功能及机制，并对其在临床上的进一步应用提出建议与展望。 Mesenchymal stem cell（MSC） is a kind of tissue stem cell having a characteristics of high self-renewal and muhipotency. It is tended to be separated in vitro and play an important role in hematopoietic stem cell transplantation and transplantation of other systems. This article described mesenchymal stem cell＇s function and mechanism on supporting hematopoiesis, enhancing implantation, adjusting immunity and alleviating graft versus host disease （GVHD） in transplantation and also give some advices and experties about its further application.
作者 唐晶晶(综述) 林艳娟(审校)
机构地区 福建医科大学附属协和医院血液科
出处 《白血病．淋巴瘤》 CAS 2009年第6期373-376,共4页 Journal of Leukemia & Lymphoma
基金 基金项目：福建省自然科学基金（2007J0084）
关键词 造血干细胞移植 间质干细胞 移植物抗宿主病 Hematopoietic stem cell transplantation Mesenchymal stem cells Graft versus host disease
分类号 R457.7 [医药卫生—治疗学] R329.2 [医药卫生—人体解剖和组织胚胎学]
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参考文献32

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二级参考文献4

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共引文献4

同被引文献9

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引证文献1

白血病．淋巴瘤
2009年 第6期

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