呼吸监护病区金黄色葡萄球菌耐药性监测(附21株资料分析)

Monitoring drug resistance of staphylococcus aureus in respiratory intensive care unit.

目的：对呼吸监护病区（ＲＩＣＵ）分离的２１株金黄色葡萄球菌（金葡菌）进行耐药性监测。方法：药敏试验采用纸片扩散法，用色原头孢菌素（ｎｉｔｒｏｃｅｆｉｎ）纸片法检测内酰胺酶。结果：ＲＩＣＵ分离的金葡菌高于普通病房，检出耐甲氧西林金葡菌（ＭＲＳＡ）１７株，ＭＲＳＡ有１２株产内酰胺酶。结论：金葡菌产酶株与非产酶株的耐药相比有差别。

Objective: To study the drug resistance of 21 strains of Staphylococcus aureus(S aureus) isolated from respirartory intensive care unit (RICU). Methods: Drug sensitivity tests were performed by disk diffusion (KB) method and lactamase was determined by Nitrocefin. Results: The detectable rate of S aureus isolated from RICU was higher than general respiratory ward. 17 out of 21 strains of S aureus were methicillinresistant Staphylococcus (MRSA), 12 strains were lactamaseproductive. Conclusion: Resistance to antibiotics was different between lactamase productive and non lactamase productive strains of S aureus vancomycin is the only antibiotics sensitive to all strains of S aureus.