81例微柱凝胶法交叉配血试验次侧凝集的临床因素分析

Analysis of clinical factors for hypo-side agglutination in 81 cases in cross match blood test with microcol- umn gel assay

目的分析使用微柱凝胶法进行交叉配血试验出现次侧凝集的各种病因,为临床输血提供指导作用。方法收集本院2007年1月至2008年10月间所有使用微柱凝胶法进行交叉配血试验次侧出现凝集,且患者红细胞直接Coombs试验抗体为阳性的患者并进行统计分析。结果81例次侧凝集的患者中大部分为肾脏疾病、肝胆疾病、血液疾病以及免疫性疾病,其中又以肾脏疾病最多,占16.2%。结论本结论对不同疾病的交叉配血试验和安全输血有一定的指导作用。

Objective To analyze the etiological factor for hypo-side agglutination in cross match blood test（CMT） with microcolumn gel assay, and to provide a guide to the clinical blood transfusion. Methods The data were collected and analyzed about 81 cases with hypo-side agglutination in CMT with microcolumn gel assay and direct antiglobulin test （DAT） positive from Jan. 2007 to Oct. 2008. Results Among the 81 hype-side agglutinated cases, most were with kidney disease, liver and gall disease, hematologic disease and immunologic disease. Specially, the kidney disease was most, accounting for 16.2%. Conclusion The analysis contributes to disposal in CMT and the safety of clinical blood transfusion.