婴儿肝炎综合征33例临床分析

The Clinical Analysis on 33 Cases of Infantile Hepatitis Syndrome

目的分析婴儿肝炎综合征的病因,临床特征及治疗效果。方法回顾性分析33例婴儿肝炎综合征的病因及临床特点,分析巨细胞病毒(CMV)肝炎和非巨细胞病毒肝炎的临床特征的差异,分析更昔洛韦治疗巨细胞病毒肝炎的疗效。结果巨细胞病毒肝炎的临床症状及实验室指标中,肝脏大小在巨细胞病毒和非巨细胞病毒肝炎存在差异,而总胆红素(TB),直接红素(DB),丙氨酸转氨酶(ALT),胆汁酸值均无显著性差异,应用更昔洛韦治疗巨细胞病毒肝炎效果显著。结论巨细胞病毒感染是婴儿肝炎综合征的主要病因,应及早应用更昔洛韦治疗,同时应加强孕妇保健及宣教工作。

Objective Probing into the pathogen,the clinical characteristics and the treatment efficacy of infantile hepatitis syndrome. Mechod By reviewing the pathogen and the clinical characteristics of 33 cases of infantile hepatitis syndrome,an attempt is made to analyze the discrepancy between the clinical characteristics of CMV hepatitis and those of non-CMV one as well as the efficacy of Gengxilnowei on treating CMV hepatitis. Results Among the clinical symptom and laboratory index of CMV hepatitis, the size of liver shows discrepancy between CMV hepatitis and non-CMV hepatitis, whereas total bilirubin（TB）,direct bilirubin （DB）, alanine transaminase（ALT）, bile acid value all shows no significant difference, thus Gengxiluowei is efficacious in treatingCMV hepatitis. Conclusion CMV infection is the main pathogen of the infantile hepatitis syndrome, so early treatment with Gengxiluowei, gravida health care and popularization is recommended.