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贝伐单抗在卵巢上皮性癌化疗中的应用进展 被引量:1

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摘要 卵巢上皮性癌(卵巢癌)是常见的妇科恶性肿瘤,居女性恶性肿瘤死亡原因的第4位。近30年来,随着化疗方案的改进,卵巢癌的5年生存率从过去的37%提高到目前的45%,但仍有75%的卵巢癌患者诊断时已属晚期(Ⅲ~Ⅳ期),经肿瘤细胞减灭术+标准一线化疗[即紫杉醇+卡铂(TC)方案]后,多数患者可获临床完全缓解,但仍有50%以上的患者复发,终因肿瘤耐药而死亡。为改善卵巢癌患者的预后,世界范围内各大肿瘤中心正致力于研究卵巢癌的不同治疗策略(如巩固治疗、腹腔化疗等)和开发新的细胞毒化疗药物及针对特异性分子靶点的生物制剂,
出处 《中华妇产科杂志》 CAS CSCD 北大核心 2009年第6期475-477,共3页 Chinese Journal of Obstetrics and Gynecology
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