A型肉毒毒素注射治疗腋窝多汗症或伴腋臭症

Treatment of axillary hyperhidrosis and bromidrosis with botulinum toxin （BTX）-A injection

目的探讨A型肉毒毒素（botulinum toxin-A，BTX—A）注射治疗腋窝多汗症或伴腋臭症及单纯液臭的疗效。方法采用BTX-A每侧腋窝注射50U治疗，注射选点25个，间距1．5cm，每点注射2．5u。结果共治疗特发性局限性腋窝多汗症或伴腋臭患者42例，其中单纯腋窝多汗症24例全部有效。腋窝多汗症伴有腋臭10例，其中注射后多汗症治疗全部有效，腋臭治疗有效者只有1例。单纯腋臭8例，碘淀粉试验阴性，注射后只有1例显效，无效7例。结论BTX-A治疗腋窝多汗症有效，副作用轻微、一过性。BTX—A治疗多汗症所伴有的腋臭疗效欠佳，对单纯的腋臭治疗基本无效。

Objective To probe the advantages of BTX-A for the treatment of axillary hyperhidrosis. Methods 42 cases were treated by BTX-A injection, 50 units per axillae, 25 sites with 2 units each, 1.5 cm apart. They consisted of 24 cases of axillary hyperhidrosis, 10 cases of axillary hyperhidrosis combined bromidrosis, and 8 cases of bromidrosis. Results All hyperhidrosis patients achieved good effects. Among patients with axillary hyperhidrosis combined bromidrosis, it had effects on hyperhidrosis, but only one case effected on bromidrosis. Among patients with bromidrosis, only one case had effect. Conclusions In the treatment of hyperhidrosis, BTX-A is very useful, and side effect is temporary and slight. But for bromidrosis, BTX-A is not very useful.