性病门诊患者泌尿生殖道支原体药敏试验结果分析

Statistic analysis on the drug resistance test results of urogenital mycoplasm from STD outpatients

目的分析我院近年来皮肤科性病门诊患者中解脲脲原体(Uu)、人型支原体(Mh)感染的耐药情况,为临床治疗提供参考依据。方法采用支原体检测试剂检测Uu、Mh,同时进行9种抗生素敏感性测试。对5年的药敏试验结果进行统计学分析。结果在三种不同感染情况下,最敏感的抗菌药物均为原始霉素、交沙霉素和强力霉素,敏感率在94%以上。结论原始霉素、交沙霉素和强力霉素目前可作为临床治疗支原体感染的首选药物;Uu和Mh的耐药谱有差异,Uu+Mh混合感染的情况下,混合耐药谱是Uu耐药谱和Mh耐药谱的交集,由Mh起主导作用;滥用抗生素是支原体耐药谱不断变化的主要原因之一。

Objective To study the drug resistance status of urogenital ureaplasma urealyticum（Uu） and myeoplasma hominis（Mh） of myeoplasma gathered from STD outpatients, and provide the reference for clinical remedy. Methods Uu and Mh were detected in mycoplasma biological test kit while drug resistance test to 9 kinds of antibiotics were carried out. The data for the past five years are statistically analyzed. Results Pristinamycin, Josamycin and Doxycycline are the most effective antibiotics in all 3 infection situation. The sensitive ratio are all above 94%. Conclusion Pristinamycin, Josamycin and Doxyeycline could be the preferred antibiotics to cure mycoplasma infection currently; There exist differences between the drug resistance spectrum of Uu and Mh; Antibiotics-abuse could be one of the main causes to induce variation in drug resistance spectrum of mycoplasma.