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散发性Creutzfeldt-Jakob病的临床和影像学特点 被引量：1

Clinical and imaging characteristics of sporadic Creutzfeldt-Jakob disease
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摘要 目的探讨散发性Creutzfeldt-Jakob病(sCJD)的临床和影像学特点。方法回顾性分析4例sCJD患者的临床资料。结果4例sCJD患者均表现为亚急性起病,进行性痴呆,伴有肌阵挛;头颅MRI显示对称性或非对称性大脑皮质彩带样和(或)基底节弥散加权成像(DWI)高信号。结论sCJD的临床特点为进展性痴呆伴肌阵挛,头颅MRI特别是DWI出现高信号为其病变特点。 Objective To study the clinical and imaging characteristics of sporadic Creutzfeldt-Jakob disease （sCJD）. Methods The clinical data of 4 patients with sCJD were analysed retrospectively. Results The clinical manifestations of the 4 cases were subacute onset, progressive dementia and accompanied with myoclonus. The skull MRI examination showed that the symmetrical or asymmetrical color zonal high signals were found in cerebral cortex and basal ganglia by diffusion-weighted imaging （ DWI ）. Conclusions The clinical characteristics of sCJD are the progressive dementia and myoclonus. The lesions characteristics is the high signals of skull MRI（espeeially DWI）.
作者 徐武 奚峰 戴晓鹏 何龙锦 赵向东 万琪
机构地区 扬州大学医学院附属泰兴人民医院神经内科 江苏省人民医院神经内科
出处 《临床神经病学杂志》 CAS 北大核心 2009年第3期206-207,共2页 Journal of Clinical Neurology
关键词 散发性Creutzfeldt—Jakob病 磁共振成像 弥散加权成像 sporadic Creutzfeldt-Jakob disease magnetic resonance imaging diffusion-weighted imaging
分类号 R742.9 [医药卫生—神经病学与精神病学]
  • 相关文献

参考文献9

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共引文献30

同被引文献13

  • 1陈惠玲,石静萍,葛剑青,刘文,逯恒东,张颖冬.散发性Creutzfeldt-Jakob病30例临床分析[J].临床神经病学杂志,2008,21(5):345-347. 被引量：5
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引证文献1

二级引证文献9

临床神经病学杂志
2009年 第3期

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