小叶黑柴胡药理作用的进一步研究

The Further Studies on the Pharmacological Actions of Bupleurum smithii var. parvifolium

小叶黑柴胡粗皂式对小鼠四氯化碳致肝损伤有显著的保护作用;乙醚提取物对冰醋酸所致小鼠扭体有明显的镇痛作用;这些作用与相同剂量的北柴胡相仿。乙醚提取物还能使小鼠胸腺增重,使小鼠血清IgG含量升高,有显著增强机体免疫功能的作用,而相同剂量的北柴胡对小鼠胸腺和血清IgG含量无显著影响。

Bupleurum smithii var. parvifoliwn grown widely in Ningxia, had a long history as a common medicinal herb. Its crude saponin had significant protective effect in hepatic damage caused by CCl4 in mice, its ether extract had significant analgesic effect. The ether extract also had significant immunological facilitation effect in mice, it could increase the thymus gland weight and the serum IgG content. These results were similar to or better than that of B. chinense and indicated that B. smithii var. parvifolium could be used as B. chinense.