健脾增免冲剂的抗癌作用及其对免疫功能的影响

The Effects of Jianpizengmian Granule on Tumor Growth and Immune Function

本文报道了健脾增免冲剂(JPZM)对荷瘤小鼠的抑瘤作用及其对免疫功能的影响。结果表明:口服JPZM对小鼠移植性肉瘤(S_(180))和肝癌(HeP_A)具有明显的抑制作用,抑瘤率达46.25％、45.57％;JPZM能明显提高荷瘤鼠的脾指数和胸腺指数,与对照组相比具有显著差异(P<0.01);能增加小鼠血清溶血素含量,并能促进小鼠脾淋巴细胞转化,两者与对照组相比具有显著的差异(P<0.05)。

The effects of Jianpizengmian (JPZM) granule on tumor growth and immune function were researched in tumor-bearing mice. The results showed it had significant inhibiting activity against S180 and HePA by oral JPZM. The inhibitory rate of JPZM reached 46.25% and 45.57%. JPZM could markedly increase the index of spleen and thymus, the level of serum hemolysin and the spleen lymphocytes transformation in tumor-bearing mice, compared to control group (H2O) respectively.