肝硬化低钠血症的临床观察

Clinical significance of the level of serum natrium in liver cirrhosis

目的探讨血钠水平在肝硬化中的临床意义。方法收集本科120例住院肝硬化患者的临床资料,分析血钠水平与Child-Pugh分级、低钾血症、肝性脑病、肝肾综合征、预后等的关系。结果血钠水平与Child-Pugh分级密切相关,血钠越低,肝功能越差(P<0.01)。低血钠常伴有低血钾,血钠越低,肝性脑病、肝肾综合征的发生率越高(P<0.01),病死率越高(P<0.01)。结论血钠水平能反映肝功能损伤程度,血钠越低,预后越差。

Objective To investigate the clinical significance of the level of serum sodium in liver cirrhosis. Methods The clinical data of 120 in-patients with hepatic cirrhosis was analyzed retrospectively, so as to investigate the relation between the level of serum sodium and the classification of Child - Pugh, the level of serum kalium, hepatic encephalopathy, hepatorenal syndrome, and prognosis. Results The levels of serum sodium were closely related to Child - Pugh classification. The lower the levels of serum sodium were, the worse the function of the liver was. （P〈0.05）. The low levels of serum sodium were usually accompanyed with the levels of serum kalium. The lower the serum sodium was, the higher the occurance of the hepatic encephalopathy and hepatorenal syndrome （P〈0.01） , and the higher rate of death was. （P〈0.01） Conclusion The levels of serum sodium can show the degree of damage of the liver function in liver cirrhosis.The lower the level of serum sodium is,the more worse the prognosis is.