术中功能区定位在切除中央沟附近胶质瘤中的应用

Application of intraoperative location of eloquent brain areas in resection of glioma near the central sulcus

目的探讨直接皮质体感诱发电位在脑中央沟附近胶质瘤切除术中的作用。方法回顾性分析32例中央沟附近胶质瘤的临床资料,均在直接皮质体感诱发电位辅助下定位,行肿瘤切除术。结果肿瘤全切除29例,次全切除3例。术后肢体功能障碍较术前减轻10例,不变11例,短期加重后肢体运动或感觉功能有所恢复8例,加重3例,无手术死亡。结论皮质体感诱发电位定位中央沟,能在最大程度切除胶质瘤的同时保护脑功能,这是一种简单可靠的定位方法。

Objective To investigate the role of somatosensory evoked potential in resection of glioma near central suleus, Methods The clinical data of 32 patients with gliomas near central sulcus was retrospectively analyzed. The glioma was located by somatosensory evoked potential and resected. Results The lesions were totally removed in 29 cases and subtotally in 3. The preoperative neurological dysfunction were improved in 10 cases, remained no change in 11, improved after transient deterioration in 8, and permanently deteriorated in 3. There was no operative mortality. Conclusion Intraoperative location of the central sulcus by somatosensory evoked potential allows a maximum resection of gliomas and protection of brain function, thus being a reliable, precise and safe method.