三维适形放射治疗肝癌55例疗效分析

Analyses of 55 cases of liver cancer treated with 3-dimentional conformal radiotherapy

目的观察评价三维适形放射治疗技术(3-DCRT)治疗原发及继发性肝癌的治疗疗效。方法1998年11月至2007年12月对55例原发及继发性肝癌患者进行3-DCRT治疗,总剂量D_T45～60Gy/15～30F,3～6w,正常肝组织V_(30)<33%。结果55例患者中,CR 6例(10.9%),PR 26例(47.3%),NC 15例(27.3%),PD 8例(14.5%),总有效率(CR+PR)58.2%。1、2、3年生存率分别为67.3%(37/55)、34.9%(15/43)、23.3%(7/30)。结论3-DCRT治疗肝癌安全有效,毒副反应小。

Objective To evaluate the treatment effect of 3-dimentional con-formal radiotherapy （3-DCRT） on the patients with primary or secondary liver cancer. Method 55 patients with primary or secondary liver cancer from November 1998 to December 2007 were treated with 3-DCRT. The total doses were DT45-60Gy/15-30F/3-6w,and the V30 of normal liver tissue was 〈 33%. Results of 55 patients, there were 6 （ 10. 9% ） patients with CR, 26 （47.3%） with PR, 15 （27.3%） with NC and 8 （ 14. 5% ） with PD. The total effective rate （CR ＋ PR） was 58.2%. The one-,two- and three-year survival rates were 67. 3% （37/55）, 34. 9% （15/43） and 23.3% （7/30） ,respectively. Conclusions 3-DCRT is effective and safe for the patients with liver cancer, and its side effect is slight.