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格列本脲继发性失效患者应用格列美脲的疗效观察 被引量:1

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摘要 对53例格列本脲继发性失效的2型糖尿病患者停用格列本脲,换用格列美脲治疗,结果:周后,FPG、2hPG和HbA1c降低(P<0·05),FINS无明显变化(P>0·05),PINS下降(P<0·05),HOMA-IR明显降低(P<0·05),BMI轻微下降但无统计学意义,TG、HDL-C较前改善(P<0·05),血压无变化。结论格列美脲因其双重的降糖作用能有效控制口服格列本脲失效的2型TDM患者的血糖,并对改善患者体重和血脂有益。
作者 杨青
出处 《实用糖尿病杂志》 2009年第3期17-18,共2页 Journal of Practical Diabetology
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