摘要
采用免疫花环法对４９例慢性肝炎患者外周血Ｔ淋巴细胞亚群进行观察，发现与正常人相比，慢性肝炎患者Ｔ３＋、Ｔ４＋，Ｔ４＋／Ｔ８＋比值明显低于正常人（Ｐ＜００１），Ｔ８＋明显高于正常人（Ｐ＜００１）；ＣＡＨ－Ｂ、ＣＰＨ－Ｂ的Ｔ３＋、Ｔ４＋、Ｔ４＋／Ｔ８＋比值亦明显低于正常人（Ｐ＜００５），Ｔ８＋明显高于正常人（Ｐ＜００５），而二组间无明显区别（Ｐ＞００５），慢性乙肝（ＣＡＨ－Ｈ、ＣＰＨ－Ｂ）患者的Ｔ淋巴细胞亚群间存在平衡失调。
The peripheral blood T-lymphocyte subsets of 49 chronic hepatitis B patients were evaluated with immuno-rossette technique.It revealed that their T 3 +、T 4 +、T 4 +/T 8 + values were much lower than those of normal control group (P<0 01),while T 8 + values was markedly higher (P<0 01);The T 3 +、T 4 +、T 4 +/T 8 + values of CAH-B、CPH-B patients were much lower,and T 8 + was much higher than those of normal controls ,too(P<0 05).The difference was insignificant between CAH-B and CPH-B group (P>0 05).In conclusion,chronic hepatitis B patients are accompanied with T-lymphocyte subsets balance disorder and functional disturbance.
