妊娠期糖尿病对妊娠结局的影响

Analysis on Gestational diabetes Mellitus and Pregnancy Outcome

目的探讨妊娠期糖尿病对妊娠结局的影响。方法回顾性分析2005年1月～2008年11月住院分娩的妊娠期糖尿病322例及健康孕妇300例的妊娠结局。结果妊娠期糖尿病组中妊娠期高血压、羊水过多、胎膜早破、剖宫产、胎儿窘迫、新生儿窒息、新生儿低血糖、巨大儿、新生儿高胆红素血症的发生率分别为16.77%、20.33%、8.07%、63.04%、12.73%、8.07%、9.93%、30.43%、9.00%,均明显高于对照组,分别为2.67%、5.67%、3.67%、24.00%、3.67%、2.67%、0.33%、2.67%、2.00%,差异有统计学意义(P<0.05)。结论妊娠期糖尿病对母婴危害大。及早诊断和治疗妊娠期糖尿病可减少母婴并发症,降低围产儿的死亡率。

Objective To evaluate the influence of gestational diabetes mellitus （GDM） on the pregnancy outcome. Methods Sixty-two women with GDM and Sixty-two nondiabetic pregnant women were investigated from January 2005 to Novmber 2008. The effect of GDM on pregnancy outcome was analyzed with comparison to the control group. Results In GDM group the incidence of hypertensive disorder complicating pregnancy,polyhydranmios,premature rupture of membrane,caesarean section,fetal dis-tress,neonatal asphyxia,neonatal hypoglycemia, factal associated, hyperbilirubinemia of newborn of and were 16.77%, 20.33%, 8.07%, 63.04%, 12.73%, 8.07%, 9.93%, 30.43% and 9.00% ,respectively. There was significant difference ascompared with the control group 2.67% ,5.67% ,3.67% ,24.00% ,3.67% ,2.67%, 0.33% ,2.67% ,2.00% ,respectively. Conclusion Pregnancy with diabetes is harmful to mother and infant. Diagnosing and treating the cases earlier can decrease the complications ofmother and infant as well as the death rate of perinatal fetus.