鹅不食草化学成分的研究

Chemical constituents from Centipeda minima

目的：研究鹅不食草Centipeda minima化学成分。方法：利用硅胶色谱,Sephadex LH-20色谱和反相HPLC等手段进行分离纯化,应用NMR等方法鉴定结构。结果：从鹅不食草中分离鉴定了10个化合物,分别鉴定为（-）-cis-chrysanthe-nol-O-β-D-glucopyranoside（1）,methy 3,5-dicaffeoylquinate（2）,3,5-Di-O-caffeoyl quinicacid（3）,tricin（4）,2-amino-4-methyl-pen-tanoicacid（5）,2-amino-3-phenyl-propionic acid（6）,4-amino-4-carboxychroman-2-one（7）,brevilin-A（8）,arnicolide C（9）,arnicol-ide D（10）。结论：其中化合物1-7为首次从该植物中分离得到。

Objective： To study the chemical constituents from Centipeda minima. Method ： The constituents were isolated by column chromatography on silica gel, Sephadex LH-20 and HPLC-ODS, and identified by spectroscopic methods. Result： Ten compounds, （ - ） -cis-chrysanthenol-O-β-D-glucopyranoside （ 1 ）, methy 3,5-dicaffeoylquinate （ 2 ）, 3,5-di-O-caffeoyl quinicacid （3）, tricin （ 4 ）, 2 -amino-4 -methyl- pentanoicacid （ 5 ）, 2 -amino-3-phenyl-propionic acid （ 6 ）, 4-amino-4-carboxychroman-2-one （ 7 ）, bre- vilin-A （8）, arnicolide C （9）, arnicolide D （10） were isolated and identified. Conclusion： Compounds 1-7 were isolated from the plant for the first time.