摘要
目的:研究鹅不食草Centipeda minima化学成分。方法:利用硅胶色谱,Sephadex LH-20色谱和反相HPLC等手段进行分离纯化,应用NMR等方法鉴定结构。结果:从鹅不食草中分离鉴定了10个化合物,分别鉴定为(-)-cis-chrysanthe-nol-O-β-D-glucopyranoside(1),methy 3,5-dicaffeoylquinate(2),3,5-Di-O-caffeoyl quinicacid(3),tricin(4),2-amino-4-methyl-pen-tanoicacid(5),2-amino-3-phenyl-propionic acid(6),4-amino-4-carboxychroman-2-one(7),brevilin-A(8),arnicolide C(9),arnicol-ide D(10)。结论:其中化合物1-7为首次从该植物中分离得到。
Objective: To study the chemical constituents from Centipeda minima. Method : The constituents were isolated by column chromatography on silica gel, Sephadex LH-20 and HPLC-ODS, and identified by spectroscopic methods. Result: Ten compounds, ( - ) -cis-chrysanthenol-O-β-D-glucopyranoside ( 1 ), methy 3,5-dicaffeoylquinate ( 2 ), 3,5-di-O-caffeoyl quinicacid (3), tricin ( 4 ), 2 -amino-4 -methyl- pentanoicacid ( 5 ), 2 -amino-3-phenyl-propionic acid ( 6 ), 4-amino-4-carboxychroman-2-one ( 7 ), bre- vilin-A (8), arnicolide C (9), arnicolide D (10) were isolated and identified. Conclusion: Compounds 1-7 were isolated from the plant for the first time.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2009年第12期1520-1522,共3页
China Journal of Chinese Materia Medica
基金
天津市应用基础研究计划项目(07JCZDJC05400)