摘要
弥漫性肺泡出血综合征（diffuse alveolar hemorrhage syndrome，DAHS）指在病因作用下，肺微血管血液进入肺泡，发生弥漫性肺泡出血（DAH），临床出现呼吸困难、咯血、贫血等症状．胸部x线片示双侧弥漫性肺泡浸润。该综合征是发生在一系列疾病过程中的严重并发症，并非一独立疾病，多来势凶险，危及生命，症状复杂。目前对于DAH尤其是自身免疫性疾病相关的DAH认识不足，常导致诊断及治疗延误，应引起临床医生高度重视。
出处
《中华风湿病学杂志》
CAS
CSCD
北大核心
2009年第6期424-426,共3页
Chinese Journal of Rheumatology
参考文献14
-
1Susarla SC,Fan LL.Diffuse alveolar hemorrhage syndromes in children.Curt Opin Pediatr,2007,19:314-320.
-
2Specks U.Diffuse alveolar hemorrhage syndromes.Curr Opin Rheumatol,2001,13:12-17.
-
3Heeringa P,Schreiber A,Falk RJ,et al.Pathagenesis of pulmonary vasculitis.Semin Respir Crit Care Med,2004,25:465-474.
-
4Lauque D,Cadranel J,Lazor R,et al.Microscopic polyangiitis with alveolar hemorrhage:a study of 29 cases and review of the literature.Medicine (Baltimore),2000,79:222-233.
-
5Schnabel A,Reuter M,Csemok E,et al.Subclinical alveolar bleeding in pulmonary vasculitides:correlation with indices of disease activity.Ear Respir J,1999,14:118-124.
-
6Thabet F,Sghiri R,Tabarki B,et al.ANCA-associated diffuse alveolar hemorrhage due to benzyithioaracil.Eur J Pediatr,2006,165:435-436.
-
7Jiang X,Khurigara G,Rubin RL.Transformatian of lupus-inducing drugs to cytotoxic products by activated neutrophils.Science,1994,266:810-813.
-
8Bucciarelli S,Espinosa G,Asherson RA,et al.The acute respiratory distress syndrome in catastrophic antiphospholipid syndrome:analysis of a series of 47 cases.Ann Rheum Dis,2006,65:81-86.
-
9Deane KD,West SG.Antiphaspholipid antibodies as a cause of pulmonary capiilaritis and diffuse alveolar hemorrhage:a case series and literature review.Semin Arthritis Rheum,2005,35:154-165.
-
10Cortese G,Nicali R,Plaeido R,et al.Radiological aspects of diffuse alveolar haemorrhage.Radiol Med,2008,113:16-28.
二级参考文献25
-
1Travis WD, Colby TV, Lombard C, et al. A clinicopathologic study of 34 cases of diffuse pulmonary hemorrhage with lung biopsy confirmation.Am J Surg Pathol, 1990,14:1112.
-
2Niles JL, Bottinger EP, Saurina GR, et al. The syndrome of lung hemorrhage and nephritis is usually an ANCA-associated condition. Arch Intern Med, 1996,156:440.
-
3Zamora MR, Wamer ML, Tuder R, et al. Diffuse alveolar hemorrhage and systemic lupus erythematosus: clinical presentation, histology, survival, and outcome. Medicine (Baltimore),1997,76:192.
-
4Albelda SM, Gefter WB, Epstein DM, et al. Diffuse pulmonary hemorrhage:a review and classification. Radiology, 1995,154:289.
-
5Izumi,Takateru.Pulmonary hemosiderosis and Good-Pasture syndrome diagnosis and treatment of diffuse infiltrative lung diaease.Kinpodo Publishers Inc., 1995.116.
-
6Schwarz MI, Zamora MR, Hodges TN, et al.Isolated pulmonary capillaritis and diffuse alveolar hemorrhage in rheumatoid arthritis and mixed connective tissue disease. Chest, 1998, 113:1609.
-
7Koh WH, Thumboo J, Boey ML. Pulmonary haemorrhage in oriental patients with systemic lupus erythematosus.Lupus, 1997,6:713.
-
8Chang MY, Fang JT, Chen YC, et al. Diffuse alveolar hemorrhage in systemic lupus erythematosus: a single center retrospective study in Taiwan. Ren Fail,2002 24(6) :791.
-
9Hughson MD, He Z, Henegar J, et al. Alveolar hemorrhage and renal microangiopathy in systemic lupus erythematosus. Arch Pathol Lab Med,2001,125(4) :47.
-
10Weber M, Pullig O, Kohler H. Distribution of Goodpasture antigens within various human basement membranes. Nephrol Dial Transplant, 1990,5:87.
共引文献10
-
1孙乐,曾抗,周再高,刁友涛,王茜.系统性红斑狼疮合并弥漫性肺泡出血三例分析[J].中华风湿病学杂志,2005,9(7):412-412.
-
2李茜,郭晓清,蒲秀红,安涛,邱萌.青年狼疮肾炎合并弥漫性肺泡出血的临床特点[J].山西医药杂志,2006,35(5):396-398.
-
3李茜,郭晓清,蒲秀红,安涛,邱萌.青少年狼疮性肾炎合并弥漫性肺泡出血的临床特点[J].中国医师进修杂志（内科版）,2006,29(6):23-25.
-
4张馨,吴燕.狼疮性肾炎患者甲基强的松龙冲击后并发肺出血[J].肾脏病与透析肾移植杂志,2006,15(3):295-300. 被引量：1
-
5鲍浩,李世军.免疫吸附治疗系统性红斑狼疮合并弥漫性肺泡出血[J].肾脏病与透析肾移植杂志,2006,15(6):584-589. 被引量：8
-
6张素,许丽杰.1例弥漫性肺泡出血病人的护理[J].护理研究（下旬版）,2007,21(11):3099-3100. 被引量：1
-
7马林浩,林兆奋,单红卫.系统性红斑狼疮合并弥漫性肺泡出血1例[J].实用医学杂志,2010,26(9):1671-1672.
-
8马林霄,邵平.系统性红斑狼疮并发弥漫性肺泡出血1例[J].哈尔滨医药,2011,31(1):46-46.
-
9妇产科.弥漫性肺泡出血合并妊娠一例[J].中华肺部疾病杂志（电子版）,2020,13(1):118-120.
-
10李贞雨,张毛,贾胜男,张倩,金珍婧.原发性胆汁性肝硬化合并肺出血1例[J].现代消化及介入诊疗,2021,26(6):802-802. 被引量：1
同被引文献59
-
1王晓陶,张中和.感染性疾病与肺泡出血综合征[J].中国实用内科杂志,2002,22(2):73-74. 被引量：5
-
2李有香.系统性红斑狼疮并发弥漫肺泡出血5例临床观察[J].中国煤炭工业医学杂志,2006,9(5):470-471. 被引量：1
-
3纪树国,张波.重视弥漫性肺泡出血综合征[J].空军总医院学报,2006,22(2):91-95. 被引量：7
-
4Schwab EP,Schucher HR Jr,Freundlich B,et al. Pulmonary alveolar hemorrhage in systemic lupus erythematosus[ J].Semin Arthritis Rheum, 1993,23 : 8.
-
5Sengul E, Eyileten T, Ozcan A, et al. Diffuse alveolar hemorrhage as an unusual presentation of systemic lupus erythematosus [ J ]. Rheumatol Int, 2011,31 (8) : 1085.
-
6Rojas-Serrano J, Pedroza J, Regalado J, et al. High prevalence of infections in patients with systemic lupus erythematosus and pulmonary haemorrhage [Jl. Lupus, 2008,17 (4) : 295.
-
7Badsha H, Teh CL, Kong KO, et al. Pulmonary hemorrhage in systemic lupus erythematosus [J]. Semin Arthritis Rheum, 2004 , 33 (6) : 414.
-
8Mart:nez-Martinez MU, Abud-Mendoza C. Predictors of mortality in diffuse alveolar haemorrhage associated with systemic lupus erythematosus[J].Lupus, 2011,20(6) : 568.
-
9Kwok SK, Moon SJ, Ju JH, et al. Diffuse alveo|ar hemorrhage in systemic lupus erythematosus- risk factors and clinical outcome: results from affiliated hospitals of Catholic University of Korea [J]. Lupus, 2011,20(1) : 102.
-
10Cafias C, Tob6n GJ, Granados M, et al. Diffuse alveolar hemorrhage in Colombian patients with systemic lupus erythematosus [J]. Clin Rheumatol,2007,26 (11):1947.
引证文献5
-
1闫丽娟,王昭.噬血细胞综合征继发凝血功能障碍的认识与研究[J].临床和实验医学杂志,2012,11(2):142-143. 被引量：6
-
2林小鸿,吴满辉,吴海东.系统性红斑狼疮并弥漫性肺泡出血17例临床分析[J].岭南急诊医学杂志,2013,18(4):257-258. 被引量：1
-
3高秀华,程晓莉,蒋超英.弥漫性肺泡出血综合征一例诊断分析[J].临床误诊误治,2013,26(12):3-5. 被引量：3
-
4黄旋珠,王丽莹,徐文艺,洪小平.结缔组织病合并弥漫性肺泡出血的护理[J].当代护士（中旬刊）,2015,22(6):30-31.
-
5林玲,陈小青.聚焦丙硫氧嘧啶安全性--弥漫性肺泡出血[J].药物不良反应杂志,2015,17(2):90-93.
二级引证文献10
-
1廖沛光.儿童噬血细胞综合征中枢神经系统病变的临床研究[J].贵阳中医学院学报,2012,34(6):140-141.
-
2郭佳,王璐,侯维纳,白松婷,孙素珂,盛光耀.凝血功能障碍对儿童噬血细胞综合征预后的影响及意义[J].中国当代儿科杂志,2014,16(5):504-507. 被引量：2
-
3周刚,安友仲,朱凤雪,沈佳伟.急性白血病化疗后弥漫性肺泡出血患者临床特点及重症支持治疗的经验总结[J].中国医药,2018,13(12):1830-1834. 被引量：3
-
4李佩章,王英,黄玲莎,朱波,劳明,赵惠柳,谭晓虹.纤维蛋白原和铁蛋白在噬血细胞综合征诊疗中的价值[J].中国医药导报,2015,12(31):131-134. 被引量：3
-
5李佩章,王英,黄玲莎,朱波,劳明,赵惠柳,谭晓虹.铁蛋白和纤维蛋白原在噬血细胞综合征疗效评价中的意义[J].医学研究杂志,2016,45(3):58-60. 被引量：8
-
6杨金荣,武坤,聂波,贺振新,杨雨宇,孙杰,曾云.成人HPS临床特征及多种细胞因子水平与预后的相关性[J].昆明医科大学学报,2021,42(12):51-58.
-
7刘瑶,张秋灵,刘恒均,王玮,何飞,徐鹏.ECMO联合俯卧位通气成功救治弥漫性肺泡出血2例并文献复习[J].国际呼吸杂志,2022,42(10):752-758.
-
8蒋沈华,李利清,虞坚尔.虞坚尔以四生汤为主辨治小儿弥漫性肺泡出血综合征的经验探讨[J].云南中医药大学学报,2023,46(4):32-35.
-
9李抗,连德德,张青玲,赵忠岩,霍鹏飞.噬血细胞综合征1例报道[J].中国实用内科杂志,2018,38(A02):104-106.
-
10卢祥云,马柯,温大蔚,辛苗苗,梁宏达.弥漫性肺泡出血在系统性红斑狼疮和ANCA相关性血管炎的临床特征比较分析[J].临床医学进展,2021,11(4):1482-1489. 被引量：1
-
1任少华.肺泡出血综合征[J].临床肺科杂志,2008,13(3):334-335. 被引量：1
-
2消化系统疾病防治专家谈[J].家庭医学（下半月）,2011(10):60-61.
-
3郑良华.肝硬化并发多器官损害56例临床分析[J].中国临床保健杂志,2004,7(6):447-447.
-
4黄玉瑛,王予川,吴悦.血栓性血小板减少性紫癜2例报告[J].贵州医药,2007,31(3):261-262.
-
5李仲启,付汉中.上消化道出血综合治疗120例分析[J].现代医药卫生,2001,17(12):1004-1005.
-
6丁江华,傅爱林,张荣艳,肖承京.血栓性血小板减少性紫癜三例诊疗体会[J].江西医学院学报,2003,43(3):126-127. 被引量：1
-
7孙辙,王芳艳,王艳兰,韩宁,黄锦.血浆置换救治血栓性血小板减少性紫癜1例[J].中国输血杂志,2010,23(S1):104-104.
-
8临床综合征的发病机制（3）[J].医学综述,2005,11(5):387-388.
-
9吴兆苏.代谢综合征的再认识[J].中华流行病学杂志,2006,27(12):1017-1018. 被引量：4
-
10任少华.肺泡出血综合征[J].世界急危重病医学杂志,2006,3(2):1193-1195.
