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疫苗中的硫柳汞与自闭症研究进展 被引量:1

Review of infantile autism and thiomersal residual in vaccine
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摘要 自闭症是一种脑部功能受损伤而引起的发育障碍,通常在幼儿二岁半以前就可以发现。自闭症患者语言理解和表达困难、难与人建立情感,对各种感官刺激反应与一般儿童表现不同。随着患者年龄、智商及患病程度的不同,症状各异。自闭症患病率约为0.2‰-1%,男女患者问比例约为5比1。导致自闭症的原因可能有多种,目前尚未找到确切的答案。曾经有人将自闭症归因于麻腮风活疫苗中的麻疹疫苗的使用,1997年美国开展的一项调查,使人们对疫苗中的硫柳汞产生怀疑,由此引发了医学界的争议。硫柳汞,英文名为Thiomersal,分子式为C9H9O232HgNaS,1930年以来作为防腐剂广泛应用于生物制品及药物制剂。
出处 《中国热带医学》 CAS 2009年第7期1365-1366,1287,共3页 China Tropical Medicine
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  • 1Centers for Disease Control and Prevention (CDC) . Thimerosal in vaccines: A joint statement of the American Academy of Pediatrics and the Public Health Service[J] . MMWR Morb Mortal Wkly Rep , 1999,48 : 563-565.
  • 2Pichichero M. E, Cemichiari E, Lopreiato J, et al. Mercury concentration s and metabolism in infants receiving vaccines containing thiomersal:a descriptive study[J]. Lancet,2002,360: 1737-1741.
  • 3WHO Statement on thiomersal The Global Advisory Committee on Vaccine Safety concludes that there is no evidence of toxicity in infants,children or adults exposed to thiomersal (containing ethyl mercury) in vaccines.
  • 4Thomas Verstraeten,Robert L. Davis,Frank DeStefano. Safety of Thimerosal - Containing Vaccines : A Two -Phased Study of Computerized Health Maintenance Organization Databases [J] . Pediatrics, 2003,112:1039-1048.
  • 5Madsen KM,Hviid A,Vestergaard M,et al. A population-based study of measles, mumps, and rubella vaccination and autism [J ] . N Engl J Med, 2002,347( 19 ) : 1477-1482.
  • 6Kreesten M . Madsen,Marlene B . Lauritsen. Thimerosal and the Occurrence of Autism:Negative Ecological Evidence From Danish Population-Based Data[J]. Pediatrics, 2003,112 : 604-606.
  • 7Stehr-Green P,Tull P,Stellfeld M,et al. Autism and thimerosalcontaining vaccines: lack of consistent evidence for an association[J]. Am J Prev Med,2003,25:101 -106.
  • 8Eric Fombonne,Rita Zakarian,Andrew Bennett,et al. Pervasive Developmental Disorders in Montreal,Quebec,Canada:Prevalence and Links With Immunizations[J]. Pediatrics,2006, 118:e139-e150.
  • 9Sarah K . Parker, Benjamin Schwartz,James Todd, et al . Thimerosal-Containing Vaccines and Autistic Spectrum Disorder:A Critical Review of Published Original Data [J]. Pediatrics, 2004,114 ( 3 ) : 793-804.
  • 10http://www.fzza.com/bbs/show.asp?id =507&bd =3&totable = 1对疫苗所进行研究的新发现给自闭症的争论火上浇油[OL].

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