静脉用地尔硫倍他乐克、硝普钠治疗主动脉夹层效果的比较

Effect of Diltiazern Injection Compared with Betaloc and Sodium Nitroprusside in Patients with Aortic Dissection

目的:研究地尔硫注射液治疗无并发症的Ⅲ型主动脉夹层的疗效。方法:临床选择无并发症的Ⅲ型主动脉夹层患者15例,用尔硫注射液进行治疗(治疗组),与传统的倍他乐克和硝普钠治疗11例(对照组)进行对比研究。结果:治疗组胸痛缓解时间明显缩短3小时胸痛缓解率明显提高(72.3%对54.5%),二者比较P<0.05。治疗组死亡率与对照组相比有明显差异(P<0.01)。结论:地尔硫射液治疗无并发症的Ⅲ型急性主动脉夹层死亡率比传统治疗低,缓解疼痛比传统治疗效果好。

Objective： To study the effect of diltiazern injection in treating aortic dissection（typeⅢ） without complications. Methods：Observed and compared the curative of treating acute aortic dissection（typeⅢ）patients, which derided into two groups. One was treatment group including fifteen patients treated by diltiazem injection,the other was control group including eleven patients treated by betaloc and sodium nitroprusside.Resuits：After three hours treatment, the pain remission rate was higher（72.3% vs 54.5%） than control group （P〈0. 05） and death rate of treatment group was lower than control group（P〈0.01）. Conclusions：The effect of diltiazern injection in treating aortic dissection（typeⅢ） without complications was better than tradition treatment on lowing the death rate and relieving the pain.