肺炎支原体与小儿反复呼吸道感染的关系

Clinical Study on the Relationship of Mycoplasma Pneumoniae and Childhood Recurrent Respiratory Infection

目的探讨肺炎支原体（MP）与儿童反复呼吸道感染的关系及其临床重要性。方法对166例反复呼吸道感染患儿用PCR方法检测咽拭子MP DNA,然后对阳性患儿以PA法检测血清中的MP IgM。对确诊为MP感染的72例患儿的临床特点进行总结和分析。结果166例患儿MP DNA阳性率57.2%（95/166）,MP IgM阳性率43.4%（72/166）,其中上呼吸道感染16例、支气管炎33例、肺炎23例,发病年龄以儿童为主,3-12岁占66.7%（48/72）,54.2%（39/72）的阳性患儿发热。结论小儿反复呼吸道感染应考虑MP感染的可能,应尽早检测MP DNA、MP IgM。

Objective To study the relationship of mycoplasma pneumoniae（MP） and recurrent respiratory infection of children. Methods The expresson of MP DNA in recurrent respiratory infection childrenfrom 2007.3 -2008.10（ total 166 cases） were detected by PCR technique and the expresson of MP IgM to MP DNA Masc. children was determined by Particle agglutination（PA）. Results 57.2% children（95/166） were discovered MP DNA Masc,43.4% children （72/166） were discovered MP IgM Masc, and the total number of 〉 3 years old children was 48 cases. Conclusion The possibility of MP infection should be considered as to recurrent respiratory infection of children and the expresson of MP DNA and MP IgM could be detected.