卵巢过度刺激综合征的预测

Prediction of ovarian hyperstimulation syndrome

目的:探讨在辅助生育治疗过程中卵巢过度刺激综合征的诱因。方法:回顾性分析该院生殖中心2006年～2008年40例中重度OHSS患者的临床及实验室指标。结果:OHSS组窦卵泡数、E2水平、获卵数较非OHSS组增高,而体重指数、FSH用量小于非OHSS组,差异有统计学意义。BMI<22.5kg/m2、基础卵泡数≥19个、HCG日E2≥5000pg/ml及获卵数≥25个时易发生OHSS。结论:在促排卵过程中,根据体重指数、基础卵泡数、E2水平及获卵数临床可预测OHSS的发生。

Objective： To explore the inducing factors of ovarian hyperstimulation syndrome （OHSS） during assisted reproduction techniques therapy. Methods ： Clinical data and experiment indexes of 40 cases with medium - severe OHSS from 2006 to 2008 were analysed retrospectively. Results ： The number of baseline follicles, E2 level in serum and number of ooeytes per retrieval in OHSS group were higher than those in non - OHSS group, while BMI and FSH dose reversed. When BMI 〈 22. 5 kg/m^2 , number of baseline follicles≥ 19, E2 level in serum on HCG day ≥ 5 000 pg/ml and number of oocytes per retrieval≥25, OHSS occurred more easily. Conclusion： In the course of controlled ovarian stimulation, BMI, number of baseline follicles, E2 level in serum and number of ooeytes per retrieval are predictive indexes.