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DcR3、Livin、TRAIL在肿瘤中作用的研究进展

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摘要 细胞凋亡与增殖的动态平衡是维系生长发育、内环境稳定和免疫调节所必需的基本过程,此平衡破坏所导致的细胞凋亡抵抗是肿瘤发生发展的重要原因之一。细胞凋亡是一个复杂的细胞程序性死亡的过程。该过程涉及一系列复杂的生化反应.受多种分子的调节.其关键分子的表达异常和功能改变与肿瘤的发生发展和转归密切相关。本文主要就细胞凋亡的机制及新近研究较多的几种凋亡诱导剂DcR3、Livin、TRAIL在肿瘤发生发展中的作用作一综述。
作者 陈春燕 龚莉
出处 《泸州医学院学报》 2009年第3期315-318,共4页 Journal of Luzhou Medical College
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