脑胶质瘤术后复发临床分析

CLINICAL ANALYSIS OF POST-OPERATIVE RECURRENCE OF NEUROSPONGIOMA

目的探讨脑胶质瘤术后复发的原因、诊断及治疗措施。方法对40例脑胶质瘤术后复发病人的临床资料进行回顾性分析。结果40例病人术后平均复发时间为7个月,原部位及原部位边缘复发者31例,远隔部位及多部位复发者9例。病理分级与原发肿瘤保持同级别者13例,级别进展者27例。手术切除全部病灶的病人预后优于病灶部分切除的病人。结论复发性胶质瘤总体预后较差,早期诊断、积极手术治疗结合术后放化疗有利于改善预后,提高病人生活质量。

Objective To analyze the causes, diagnosis and treatments of post-operative recurrence of neurospongioma. Methods A retrospective study of 40 patients with recurrent neurospongioma conducted. Results The mean time of post operative recurrence was seven months, in which, 31 cases recurred in virgin location or at the margin, nine in remote or of multiple locations. The pathologic staging was the same as the previous was recorded in 13 cases, and increased staging recorded in 27 cases. The prognosis of patients received total resection of the focus was better than those underwent partial removal. Conclusion The prognosis of recurrent neurospongioma is poor. Early diagnosis and surgery combined with post-operative chemo-and radiotherapy are conducive to prognosis and improving patients＇ quality of life.