^(99m)Tc-MIBI双时相显像在原发性甲状旁腺功能亢进症术前定位诊断中的价值

Preoperative localization diagnosis of primary hyperparathyroidism by using ^(99m)Tc-MIBI double-phase imaging

目的对99mTc-MIBI双时相显像与颈部超声和颈部CT在原发性甲状旁腺功能亢进症术前定位诊断价值进行对比研究。方法回顾性分析了44例经病理确诊为原发性甲状旁腺功能亢进症患者,术前甲状旁腺激素检测结果并将术前的99mTc-MIBI双时相显像、颈部超声及颈部CT检查结果进行对比分析。结果甲状旁腺激素检出率为100%,但不可进行定位诊断;99mTc-MIBI双时相显像、颈部超声及颈部CT均可进行定位诊断;99mTc-MIBI双时相显像检出率(93.18%)分别高于颈部超声及颈部CT检出率(63.64%,61.9%),差异有统计学意义(P<0.05);颈部超声与颈部CT检出率,差异无统计学意义(P>0.05)。结论99mTc-MIBI双时相显像在原发性甲状旁腺功能亢进症中有较好的术前定位诊断价值。

Objective To contrast the value between ^99mTc-MIBI dual-phase imaging and neck ultrasound or CT in the preoperative localization diagnosis of primary hyperpmathyroidism. Methods Retrospective analyzed the Preoperative parathyroid hormone test results of 44 hyperparathyroidism Patients and Comparative Analyzed the results of ^99mTc-MIBI dual-phase imaging and neck ultrasound and CT. Results The rate of detecting Parathyroid hormone was 100%, but it can not be used in positioning diagnosis; the ^99mTc- MIBI dual-phase imaging and neck ultrasound and CT can be used in positioning diagnosis; the detection rate of ^99mTc-MIBI dual- phase imaging（93.18% ） were higher than the neck ultrasound and CT（63.64% ,61.9% ） respectively;the difference was significant （ P 〈 0.05） ; the difference of neck ultrasound and CT detection rate was not significant（ P 〉 0.05） ble-phase imaging has the value in Preoperative localization of primary hyperparathyroidism.