脑卒中并发感染对神经功能恢复的影响

Complicated Infection on Functional Outcome of Stroke

目的探讨急性脑卒中并发感染对患者神经功能恢复的影响。方法225例脑卒中患者分为无感染组(145例)和感染组(80例)。分别给予相应药物治疗。记录入院时体温及住院期间最高体温,评估出院时巴氏指数(BI),改良的Rankin量表评分(mRS)和美国国立卫生研究所脑卒中评分(NIHSS)。结果住院期间,感染组的最高体温明显高于无感染组(P<0.01),年龄明显大于无感染组(P<0.01),住院时间明显长于无感染组(P<0.05)。出院时感染组减少的NIHSS百分数明显低于无感染组(P<0.01),mRS明显高于无感染组(P<0.01)。结论卒中后并发感染影响急性脑卒中患者的神经功能恢复。脑卒中并发感染患者的神经功能恢复较未并发感染者差。

Objective To observe the influence of complicated infections on functional outcome of patients with stroke. Methods Two hundred and twenty five stroke patiens confirmed by cranial CT scan or MR were prospectively divided into non-infection （145 cases） and infection （80 cases） groups. The body temperature of all the patients was recorded on admission and during hospitalization, the National Institutes of Health Stroke Scale（NIHSS）, Barthel Index（BI） and modified Rankin Scale（mRS） were documented in all the cases. The difference in functioual outcome between the two groups was analyzed. Results The maximun body temperature of infection group was higher than that of the non-infection during hospitalization（P 〈0. 01）. The funtional outcome of the patients complicated with infections was significantly worse than that of the cases without infections assessed by BI（P 〈0. 01）, mRS（P〈0. 01） and NIHSS（P 〈0. 01）. Conclusion Infection of the stroke patients influenceed functional outcome and the prognosis.