AcrySof IQ非球面人工晶状体植入后视觉质量观察

Comparison of contrast sensitivity and wavefront analysis after implantation of AcrySof IQ aspberical intraocalar lens

目的对比研究Acfysof IQ非球面人工晶状体和AcwSd Natural人工晶状体在年龄相关性白内障患者手术后的视觉质量。方法前瞻性随机对照研究。选取年龄相关性白内障患者，按照双盲原则分为两组：IQ组和Natural组，分别植入AcwSofIQ和AcwSofNatural人工晶状体，其中IQ组：124只眼；Natural组：136只眼。术后观察两组患者的最佳矫正远视力、对比敏感度（CS）值、波阵面像差。采用统计软件SPSS11．0进行数据分析，两组间术后视力采用重复测量方差分析，CS、波阵面像差采用具有一个重复测量两因素设计定量资料方差分析。结果术后1周、1个月、3个月采用CGT-1000CS眩光测试仪检查发现两组间的CS值在中、高空间频率段均有差异（F值范围5．05～26．47，P〈0．05），低频空间两组间差异随时间推移逐渐明显。两组的波阵面像差检查显示4．0mm和6．0mm瞳孔时，两组的总均方根值有差异（F值范围6．373～10．679，P〈0．05）。两组的C7、C8的均方根值差异无统计学意义（F值范围0．144—2．493，P〉0．05）。两组C12的均方根值差异有统计学意义（F值范围7．005～12．24，P〈0．05）。结论与AcwSofNatural人工晶状体相比较，AcwSofIQ可以有效地提高CS，减少白内障术后全眼像差和高阶像差，改善患者术后视觉质量。

Objective To determine vision quality when testing two acrylic intraocular lenses, AcrySof IQ and AcrySof Natural, after routine cataract extraction and IOL implantation. Method Prospective,randomized, double-masked study that 260 eyes of 260 patients who underwent cataract extraction and IOL implantation was performed. Patients were randomly divided into 2 groups ： AcrySof IQ or AcrySof Natural. One week, one and three month postoperative evaluations included contrast sensitivity and wavefront analysis. The independent-samples T test was used. P 〈 0. 05 was considered statistically significant. Result The AcrySof IQ group has significantly higher and middle spatial frequency of contrast sensitivity. The difference in low spatial frequency was getting significant along with time. Patients with AcrySof IQ had a reduction in total high-order aberrations and spherical aberration. There were no difference in coma between two groups. Conclusion The use of aspheric acrylic AcrySof IQ IOL may improve the quality of vision as a result of the reduction of contrast sensitivity and spherical aberration.