维吾尔族与汉族早发冠心病患者冠状动脉病变的临床研究

Clinical study on coronary artery lesion between Han and Uygur nationality patients with premature coronary artery disease

目的:探讨维吾尔族和汉族早发冠心病患者的心血管危险因素及冠状动脉病变的差异。方法:回顾性分析早发冠心病患者956例临床资料,分为维吾尔族组586例和汉族组370例。对2组4个常见心血管危险因素(高血压、糖尿病、血脂异常和吸烟史)及冠状动脉病变特征进行对比分析。结果:维吾尔族组糖尿病、心肌梗死比例高于汉族组,而高血压比例低于汉族组,2组比较差异均有统计学意义(P<0.05)。2组患者A型病变率最高,维吾尔族组B型、C型病变高于汉族组,而A型病变低于汉族组,差异均有统计学意义(P<0.05)。维吾尔族组3支病变高于汉族组,而单支病变低于汉族组,差异有统计学意义(P<0.05)。结论:维吾尔族早发冠心病患者糖尿病比例高于汉族。维吾尔族早发冠心病患者3支病变率高,C型病变多,冠状动脉病变严重程度较汉族早发冠心病患者重。

Objective To explore the difference of risk factors and coronary artery lesion between Han nationality and Uygur nationality patients with premature coronary heart disease. Methods A total of 956 patients with premature coronary heart disease were divided into Uygur group （586 cases） and Han group （370 cases）. The risk factors for premature coronary heart disease including diabetes, dyslipidemia, hypertension and smoking history were compared with coronary artery lesion characteristics. Results Compared with Han group, Uygur group had higher prevalence rate of diabetes and myocardial infarction, but lower prevalence rate of hypertension（P^0.05）. The rate of type A was the high in both Han and Uygur groups. Compared with the Han group, the rates of type B and C were higher, and the rate of type A was lower in Uygur group. The incidence of three-vessel lesions was significantly lower in Han group than that in Uygur group, and the incidence of the single- vessel lesion was higher. There was a statistic difference（P^0.05）. Conclusion Uygur nationality patients with premature coronary heart disease are more prone to suffering from diabetes mellitus than Han nationality patients. The coronary artery lesions of Uygur nationality patients with premature coronary heart disease are more severe than those of Han nationality patients, and there are more three-branch lesions and more type C lesion cases.