血小板指标与冠心病关系的临床研究

Clinical Study of Relation between Platelet and Angina Pectoris

目的:研究血小板指标在稳定型心绞痛(SAP),不稳定型心绞痛(UAP)和急性心肌梗死(AMI)发病中的临床意义。方法:随机选择对照组30例、SAP组28例、UAP组19例、AMI组21例,共98例病人测定血小板计数(PLT)、血小板平均体积(MPV)。统计结果由SAS软件分析。结果:UAP组和AMI组患者的PLT分别为161.84±35.67(×109/L)和137.55±28.19(×109/L),明显低于对照组(P<0.01)。SAP组、UAP组和AMI组患者的MPV分别为8.79±1.86(fl)、9.81±1.47(fl)、10.94±1.73(fl)均不同程度的高于对照组。其中UAP组和AMI组增人更显著(P<0.01)。结论:血小板指标检测对判断SAP、UAP和AMI的发生及预后有一定的临床价值。UAP、AMI的PLT和MPV变化与其病变程度有关。

Objective：To investigate the clinic effect of platelet among the occurrence of stable angina pectoris（SAP）, unstable angina pectoris（UAP） and acute myocardial infarctions（AMI）. Methods： 98 cases selected randomly were examined including thirty control SAP cases, 19 UAP cases and 21 cases of AMI. 28 Platelet count （PLT） and mean platelet volume （MPV） were tested. The statistics results were analyzed by SAS software. Results：The PLT in UAP and AM[ groups were 161.84±35.67（ X 109/L） and 137.55±28. 19（X 109/L） and they were significantly lower than that in controls （P〈0. 01）. The MPV in SAP,UAP and AMI groups were respectively 8. 79±1.86（fl）,9. 81±1.47（fl） and 10. 94±1.73（fl） and they were all higher than that in controls, among them UAP and AMI groups are significantly increased （P〈0. 01）. Conclusion： The platelet test had certain clinical value in determining occurrence and prognosis of SAP,UAP and AMI disease. The change of PLT and MPV in UAP and AMZ disease had something to do with the content of pathological changes.