摘要
Toll样受体(Toll like receptors,TLRs)是近年发现并倍受关注的一种识别受体。人们发现其在先天性和获得性免疫应答过程中起到链接点的作用,因此,TLRs在免疫学领域内具有重要地位。目前对TLRs的研究涉及到其结构、配体、信号通路以及临床应用等。现就TLRs目前的研究进展作一综述。
Toll-like receptors （TLRs） are one of pathogen recognition receptors which have been discovered and focused in recent years. TLRs play an important role in junction of innate immunity and adaptive inununity. Recent researches of TLRs involve in their structure, ligand, signaling pathways and clinical application. This review will focus on the research progress in TLRs.
出处
《细胞生物学杂志》
CSCD
2009年第3期339-343,共5页
Chinese Journal of Cell Biology
基金
国家自然科学基金资助项目(No.30800812)~~
关键词
TOLL样受体
免疫
结构
配体
信号通路
Toll-like receptors
immunity
structure
ligands
signaling pathways
