摘要
[目的]探讨目前国内外最普遍应用的"γ"射线照射消毒法对人肌腱生物力学的影响。[方法]将等长的24条肱二头肌肌腱长头配对分成两组,A组(12):非照射组,B组(12):经2.5Mrad"γ"射线照射组。采用WDW-3020电子万能材料试验机测定结构力学和材料力学。[结果]经拉伸实验后肌腱平均长度B组为A组的99.15%,最大拉长量为93.46%,刚度为95.27%,最大载荷能量为93.60%,最大应力为84.88%,最大应变为85.82%,弹性模量为90.40%,能量密度为66.73%,B组照射组与A组非照组比较P<0.05,有统计学意义,照射后生物力学各参数明显降低。[结论]"γ"射线照射消毒后肌腱强度明显降低,是否采用"γ"射线照射消毒同种异体组织有待于进一步研究。
[ Objective ] To explore the change of biomechanics about human tendon with "γ" irradiated which was universal used by domestic and foreign. [ Methods ] Twenty - four upper limb tendon of human with the same length were divided into two groups, group A ( 12 ) : nonirradiated group, group B ( 12 ) : 2. 5 Mrad gamma irradiated group. Material properties and structural properties were determined with WDW- 3020 electron universal testing machine. E Results] The mean length of the tendon was 99.15% of control, the elongation to failure was 93.46%, the linear stiffness was 95.27%, the energy to maximum force was 93.60% , the maximum stress was 84. 88% , the strain to failure was 85.82% , the linear modulus was 90.40%, the strain energy density to maximum was 66. 73 %. Difference was noted after compared hetween group A and B (P 〈 0. 05 ) . All biomechanical parameter presented significantly decline after irradiated. [ Conclusion ] The tendon strength reduced obvi- ously after irradiated, it needs further studies whether disinfect allograft could be irradiated with Gamma radiation on clinical.
出处
《中国矫形外科杂志》
CAS
CSCD
北大核心
2009年第13期1010-1012,共3页
Orthopedic Journal of China
关键词
生物力学
人
交叉韧带
移植
同种异体
照射
肌腱
biomechanics
human
cruciate ligament
transplant
allograft
irradiate
tendon