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大肠癌肝转移病人血清白细胞介素-4、6水平变化及其意义 被引量:1

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摘要 目的探讨大肠癌肝转移病人血清白细胞介素-4、6水平变化及其意义。方法对45例大肠癌患者进行血清中IL-4,IL-6水平含量测定。结果大肠癌肝转移组和大肠癌无肝转移组血清中IL-4,IL-6水平高于正常对照组(P〈0.05),大肠癌肝转移组血清中IL-d,IL-6水平明显高于大肠癌无肝转移组(P〈0.01)。结论联合检测血清中IL-4,IL-6水平变化可对大肠癌肝转移早期诊断可能有筛选作用。
出处 《中国医师杂志》 CAS 2009年第6期836-837,共2页 Journal of Chinese Physician
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  • 1Zhang GJ, Adachi I. Serum interleukin-6 levels correlate to tumor progression and prognosis in metastatic breast carcinoma. Anticancer Res 1999; 19: 1427-1432.
  • 2Barth RJ Jr, Camp BJ, Martuscello TA, Dain BJ, Memoli VA. The cytokine microenvironment of human colon carcinoma. Lymphocyte expression of tumor necrosis factor-a and interleukin-4 predicts improved survival. Cancer 1996; 78: 1168-1178.
  • 3Etoh T, Shibuta K, Barnard GF, Kitano S, Mori M. Angiogenin expression in human colorectal cancer: The role of focal macrophage infiltration. Clin Cancer Res 2000; 6: 3545-3551.
  • 4Minami S, Furui J, Kanematsu T. Role of carcinoembryonic antigen in the progression of colon cancer cells that express carbohydrate antigen. Cancer Res 2001; 61: 2732-2735.
  • 5Suzuki S, Mita S, Kamohara H, Sakamoto K, Ishiko T, Ogawa M. IL-6 and IFN-g regulation of IL-10 production by human colon carcinoma cells. Int J Oncol 2001; 18: 581-586.
  • 6Staal-van den Brekel AJ, Dentener MA, Schols AM, Buurman WA, Wouters EF. Increased resting energy expenditure and weight loss are related to a systemic inflammatory response in lung cancer patients. J Clin Oncol 1995; 13: 2600-2605.
  • 7Castell JV, Gomez-Lechon MJ, David M, Fabra R, Trullenque R, Heinrich PC. Acute phase response of human hepatocyte: Regulation of acute-phase protein synthesis by interleukin-6. Hepatology 1990; 12: 1179-1186.
  • 8Nozoe T, Matsumata T, Sugimachi K. Preoperative elevation of serum C-reactive protein is related to impaired immunity in patients with colorectal cancer. Am J Clin Oncol 2000; 23: 263-266.
  • 9Nozoe T, Matsumata T, Kitamura M, Sugimachi K. Significance of preoperative elevation of serum C-reactive protein as an indicator for prognosis in colorectal cancer. Am J Surg 1998; 176: 335-338.
  • 10McMillan DC, Wotherspoon HA, Fearon KCH, Sturgeon C, Cooke TG, McArdle CS. A prospective study of tumor recurrence and acute-phase response after apparently curative colorectal surgery. Am J Surg 1995; 170: 319-322.

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