鼻塞持续气道正压通气治疗早产儿呼吸暂停42例分析

Clinical Analysis of Nasal Continuous Positive Airway Pressure Therapy on 42 Cases Apnea of Prematurity

目的:评价鼻塞持续气道正压通气(NCPAP)治疗早产儿呼吸暂停(apnea of prematurity,AOP)的疗效。方法:82例呼吸暂停的早产儿随机分为两组,治疗组42例用NCPAP,对照组40例用氨茶碱加纳络酮,观察比较两组疗效。结果:治疗组的显效率、总有效率分别为61.9%、92.8%,对照组为32.5%、67.5%,两组差异具有统计学意义(P<0.01)。结论:NCPAP可有效治疗AOP,且疗效优于氨茶碱加纳络酮。

Objective： To explore the efficacy of nasal continuous positive airway pressure （NCPAP） on the treatment of the apnea of prematura（AOP）. Method： Eighty two cases with AOP were randomly divided into two groups, forty-two cases in the treatment group were used NCPAP. Forty cases in the control group were used aminophylline and naloxone. The effect of two groups were compared. Result： The markedly effective rate and the total effective rate of the treatment group were 61.9% and 92.8% respectively, while the control group were 32.0% and 67.5% respectively. It had statistical difference between two groups （P 〈 0.01 ）. Conclusion： NCPAP can treat AOP effectively and the efficacy is better than that of aminophylline and naloxone.