两种不同肠道清洁剂用于排泄性尿路造影的效果比较

Effect Comparison of Two Different Bowel Cleanser Application in Intravenous Urography

目的比较番泻叶中药配方颗粒(广东一方制药有限公司)和甘露醇两种肠道清洁剂用于排泄性尿路造影检查(IVP)的肠道清洁效果。方法将来院作IVP检查患者(n=252例)随机分为两组。A组:(n=126)给予番泻叶中药配方颗粒10～20g溶解于500ml80～90℃水中,待水温合适后一次喝下。B组:(n=126)给予20%甘露醇250ml加生理盐水或5%葡萄糖500ml口服,(根据医生习惯)。观察两组肠道清洁度,不良反应,排便开始时间和排便次数。结果A组肠道清洁度较B组好,不良反应发生轻,排便次数相对较少,经统计学分析,均P<0.005,差异有统计学意义。结论番泻叶中药配方颗粒与甘露醇相比较更适合作IVP检查前肠道清洁剂。

Objective To compare the effect of Mannitol and Senna leaf granules （Chinese traditional medicine from Guangdong YiFang Pharmacy limited Company ） which apply in intravenous urography（IVP）. Methods The patients （n = 252cases） suffered IVP are divided into two groups randomly. Group A （ n = 126） ： 10 - 20g Senna leaf granules was dissolved into 500ml water of 80°- 90℃ ,then ask the patient drink all one time when the water with proper temperature. Group B （n = 126） ：20% Mannitol 250ml dissolved into physiological saline solution or glucose solution 500ml, ask the patient drink it in proper time, （ according to the custom of each doctor）. The bowel cleaning extent, side effect, defecation time and defecation times of each group were observed. Results The bowel cleaning extent in group A is better than that of group B. Side effect is mild and defecation time is fewer in group A. Statistical analysis was done in all cases, P 〈 0. 005. The difference has statistical value. Conclusion Comparing with Mannitol, Senna leaf granules is more proper as a bowel cleanser before intravenous urography.